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Resumen de Ojo seco: clasificación clínica y por citología de impresión

Juan Murube del Castillo, Luis Rivas Jara

  • Clinical classification of dry eye (Grade 1 or subclinical: symptoms only in overexposure. Grade 2 or mild: symptoms in normal environments. Grade 3 or moderate: symptoms and reversible signs. Grade 4 or severe: symptoms and irreversible signs. Grade 5 or disabling: symptoms, signs and visual incapacity) has a numerical correlation (number to number) with impression cytology classification (Grade 1: goblet cells 300-400 cells/mm2 with PAS-positive cytoplasm, non secretory conjunctival cells with a size of 200-350 µm2, and N:C ratio of 1:3-1:4; corneal cells with an area of 300-400 µm2 and N:C ratio of 1:4. Grade 2: goblet cells 200-300 cells/mm2 with PAS-positive cytoplasm, non secretory conjunctival cells with a size of 350-500 µm2 and N:C ratio of 1:5; corneal cells with an area of 500-1000 µm2 and N:C ratio of 1:8. Grade 3: goblet cells 50-200 cells/mm2 with PAS-positive cytoplasm, non secretory conjunctival cells with a size of 500-900 µm2 and N:C ratio of 1:10; corneal cells with an area of 1000-1800 µm2 and N:C ratio of 1:15. Grade 4: goblet cells 10-50 cells/mm2 with PAS-negative cytoplasm, non secretory conjunctival cells with a size of 900-1600 µm2 and N:C ratio of 1:20; corneal cells with an area of 1800-2500 µm2 and N:C ratio of 1:20. Grade 5: goblet cells less than 10 cells/mm2 with PAS-positive cytoplasm, non secretory conjunctival cells with a size of more than 1600 µm2 and N:C ratio of 1:30; corneal cells with an area of more than 2500 µm2 and N:C ratio of 1:30; cytoplasm is keratinized).


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