A bibliographic review is made on cystoid macular edema of iatrogenic origin. Initially, it is found to be related to surgery, specially the intra-capsular extraction of the crystalline lens, with reduced incidence with extra-capsular extraction and particularly after phacoemulsification. A reduction of clinical as well as angiographic incidence is observed with the topical application of AINES. Even though the incidence is smaller, it may arise in the post-op of any surgical intervention of the anterior segment and vitreous-retina and also after laser application, particularly capsulotomy with Nd-YAG.
It is also related to anti-glaucomatose drugs, initially described after topical epinephrine, it was found associated to any anti-glaucomatose medication. Its incidence increases after epinephrine and dipivalilepinephrine, found in eye hypotensor lipids (prostaglandins); it has also been related to preservatives, particularly benzalconium chloride. It can be prevented, and in early detections becomes reversible, by the utilisation of AINES.
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