Gripe aviar: Situación actual

• Autores: José Antonio Cabezas Fernández del Campo
• Localización: Anales de la Real Academia Nacional de Farmacia, ISSN-e 1697-4298, ISSN 0034-0618, Nº. 4 2, 2006, págs. 301-315
• Idioma: español
• Títulos paralelos:
  • Avian influenza: Situation at present
• Enlaces
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• Resumen

  • This communication, which follows and amplifies previous papers by the author, published by the Real Academia Nacional de Farmacia, as indicated on its web page (www.ranf.com), is mainly concerned with the following issues: a) The role of the influenza viral glycoprotein named hemagglutinin (HA) in the selective binding and entry of this virus into the host cell; and also how certain modifications in the structure of this glycoprotein influence the pathogenicity of the avian influenza H5N1 subtype virus. b) The mechanisms of avian influenza transmission both by reassortment of genes from several sources and by gene mutation. c) The present danger for birds and humans arising from the infectivity of the H5N1 virus. d) The use of resources and drugs �excluding those related to the inhibition of neuraminidase, NA (since they will be addressed in a forthcoming publication by the author)� to combat the eventual risk of epidemies/ pandemic.