Kinesin-8s: motoring and depolymerizing

• Claire E. Walczak ^[1]
  1. [1] Indiana University System

     Indiana University System

     Township of Bloomington, Estados Unidos

     
• Localización: Nature: Cell biology, ISSN 1465-7392, Nº. 9, 2006, págs. 903-905
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Kinesins conventionally act as molecular motor proteins that translocate along microtubules. However, several kinesins also control microtubule polymerization dynamics. New work shows that the yeast kinesin-8 Kip3p has a unique combination of plus-end motor and plus-end depolymerase activities. These activities facilitate the positioning of the mitotic spindle at the cell cortex.