Luis Gómez Pellico, I. Fernández Tresguerres, A.F. Tresguerres, Rosa Rodríguez Torres, Celia Clemente de Arriba
Many factors can modify osteointegration, among them the subject's age and the possibility of using hormone treatment to improve the phenomenon. In the present study we used a histological technique that permits study not only of interface, but also bone response in distant areas. Growth hormone (GH) was used topically in aged animals that had received a titanium plate as an implant in their tibiae. A similar degree of osteointegration was observed in both, the control and treated groups. Distantly located bone issue urderwent certain modifications in its osteocyte lacunae in the treated group but not in the control group.
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