Malaria is a disease caused by a Plasmodium parasite, transmitted by the bite of an infected mosquito. With the objective of determining the behavior of malaria from January 2020 to December 2021 in the municipality of Cacolo, Lunda Sul, Angola, a cross-sectional descriptive observational study was carried out. The universe was made up of 26 252 patients and the sample was made up of 11 506 patients, having the approval of the institution and consent to carry out this work. The female sex predominated with 63,0% and the age group of 15-19 years with 14,1%; 98,4% of the patients reported fever; 96,5% were uncomplicated cases of malaria; the most used drug combination was Artemether/Lumefantrine (52,6%); 16,3% of pregnant women had at least one episode of malaria; complications predominated in the female sex 57,8%; the most frequent complication was cerebral malaria with 48,8% and there were 0,3% deaths.
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