Mild Autonomous Cortisol Secretion: Approach to Diagnosis, Evaluation, and Management

• Autores: Catherine de Martel, Hershel Raff
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 55, Nº. 2, 2026, págs. 259-269
• Idioma: inglés
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• Resumen

  • MACS is the most common hormone abnormality diagnosed in patients with adrenal nodules and is associated with increased risk for cardiometabolic disease, vertebral fractures, and mortality. While adrenalectomy may improve cardiometabolic complications in select patients with MACS, decisions about management should be individualized based on the presence of relevant comorbidities and patient characteristics. Patients with MACS who undergo conservative monitoring should have proactive screening