Regenerative Medicine and Tissue Engineering: Innovations in Scaffolding Technologies, Stem Cell Engineering, and Bioprinting for Tissue Repair and Organ Regeneration

• Llorente-Nuñez, Esteban ^[1] ; Nunes-Coelho, Diago ^[2]
  1. [1] Universidad Autónoma de Madrid

     Universidad Autónoma de Madrid

     Madrid, España

     
  2. [2] Universidade de Coimbra

     Universidade de Coimbra

     Coimbra (Sé Nova), Portugal

     
• Localización: SAP Biomedical & Chemical Engineering Innovation, ISSN-e 3125-2281, Nº. 4, 2025
• Idioma: inglés
• Enlaces
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• Resumen

  • Introduction: regenerative medicine and tissue engineering are emerging disciplines that seek to restore the function of damaged tissues and organs through technological innovations. These areas combine biology, engineering, and medicine to develop solutions that improve patients' quality of life. In this context, scaffolding technologies, stem cell engineering, and bioprinting stand out as key tools for tissue repair and organ regeneration.Development: scaffolds are three-dimensional structures that provide physical support for cell growth and tissue formation. They can be designed with biocompatible materials that mimic the properties of natural tissue, facilitating integration with the body. Stem cell engineering, on the other hand, allows for the extraction and differentiation of cells with regenerative potential, which is crucial for repairing damage to specific tissues. Bioprinting, an innovative technique, uses 3D printers to create complex cellular structures, enabling the manufacture of personalized tissues and artificial organs. These technologies have shown promising results in preclinical and clinical studies, offering new hope in the treatment of degenerative diseases, traumatic injuries, and birth defects.Conclusions: innovations in scaffolding technologies, stem cell engineering, and bioprinting are opening up new possibilities for tissue and organ repair and regeneration. As these technologies continue to evolve, it is critical to address the associated ethical and regulatory challenges to ensure their safe and effective implementation in clinical practice.