Utility of immunoinformatics in epitope mapping for vaccine and therapeutic design

• Miló Valdés, Carlos Alfredo ^[1] ; Pérez Acevedo, Lidia Cecilia ^[2] ; Vitón Castillo, Adrián Alejandro ^[1]
  1. [1] Universidad de Ciencias Médicas de Pinar del Río. Hospital Pediátrico Provincial Docente “Pepe Portilla”, Departamento de Inmunología. Pinar del Río, Cuba.
  2. [2] Centro de Inmunología Molecular. La Habana, Cuba.
• Localización: SAP Biomedical & Chemical Engineering Innovation, ISSN-e 3125-2281, Nº. 4, 2025
• Idioma: inglés
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• Resumen

  • Epitope identification is largely the basis for the development of new vaccine candidates and immunotherapies. However, traditional methods for epitope identification present certain limitations in terms of time and high costs, hence experimentation in this field is targeted and rationalized. The development of omics, as well as the introduction of bioinformatics techniques and tools in biomedical specialties, has allowed the development of immunoinformatics, which has the capacity to speed up the discovery process. The present communication aims to describe the potential of immunoinformatics in epitope mapping for the design of vaccines and therapies.