Bibliographic review on the application of biomaterials in neurological disorders

• Auza-Santivañez, Jhossmar Cristians ^[2] ; Bautista-Vanegas, Freddy Ednildon ^[3] ; Carías , Alejandro ^[1] ; Apaza Huanca, Blas ^[4] ; Sosa Remón , Ariel ^[5] ; Condo-Gutierrez , Adalid Rimer ^[6] ; Mamani Manzaneda , Laura Pamela ^[4] ; Tecuatl Gómez , Luis Mariano ^[7] ; Oberson Santander , Isaura ^[8] ; Condori-Villca , Nayra ^[9] ; Aguilar-Medrano , Fidel ^[10]
  1. [1] Universidad Nacional Autónoma de Honduras

     Universidad Nacional Autónoma de Honduras

     Honduras

     
  2. [2] Ministerio de Salud y Deportes. Instituto Académico Científico Quispe-Cornejo. La Paz, Bolivia.
  3. [3] Neurologisches Fachkrankenhaus für Bewegungsstörungen / Parkinson: Beelitz Heilstätten, Brandenburg, DE. Germany
  4. [4] Ministerio de Salud y Deportes. La Paz, Bolivia
  5. [5] Instituto Nacional de Oncología y Radiobiología. Habana, Cuba
  6. [6] Associação da família OGS saúde. EMS equipo multidisciplinar de saúde. Brazil
  7. [7] ISSSTE San José del Cabo. Universidad De Los Cabos. México
  8. [8] Hôpitaux Universitaires de Genève (HUG). Genève, Switzerland
  9. [9] Red de Salud Yacuiba. Servicio Endocrinología. Tarija, Bolivia
  10. [10] Hospital Municipal de Morón “Ostaciana B. de Lavignolle”. Departamento Medicina Interna. Buenos Aires, Argentina

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• Localización: SAP Biomedical & Chemical Engineering Innovation, ISSN-e 3125-2281, Nº. 3, 2024
• Idioma: inglés
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• Resumen

  • Introduction: the process of endogenous neurogenesis is not capable of replenishing lost cells after an injury that can result in massive cell loss. Biomaterials are being developed to mimic the brain’s extracellular matrix, providing scaffolds that promote tissue repair and regeneration. The objective was to characterize the application of biomaterials in neurological affections.Methods: a literature review was conducted, where 20 articles in English and Spanish were selected, published in the last five years on the subject, in databases such as: Scopus, PubMed, Springer.Results: biomaterials play an essential role in the human body by serving as artificial substitutes or implants that interact with living tissues, organs, and bodily fluids. Emerging approaches, including stem cell therapy, biomaterials, immune cell therapy, and exosome-based treatments, show promise in modulating the inflammatory response while avoiding broad suppression of immune function. With that in mind, researchers are exploring how these materials could help repair nerve damage once thought to be permanent, boost brain function, and play a key role in fields like neuro-oncology and neuro-rehabilitation. Conclusions: biomaterials enable safe contact with living tissue and offer promise in neuroscience. Research is still needed to address ethics and ensure safe use.