Ectopic pregnancy treated with Methotrexate, case report

• Chávez Moya, Maikro Osvaldo ^[1] ; Saez Puig, Liz Thalía ^[1] ; Cepero González, Arianny ^[1] ; Cepero Peña, Roxana ^[1] ; Córdova Guillén, Daniela Dignorah ^[1] ; Chirino Yanes, Danay ^[1] ; Hernández Cabrera, Leodanis ^[1]
  1. [1] Universidad de Ciencias Médicas de Villa Clara, Facultad de Medicina. Santa Clara, Cuba
• Localización: SAP Primary Care, ISSN-e 3121-2212, Nº. 2, 2026
• Idioma: inglés
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• Resumen

  • Introduction: ectopic pregnancy is defined as the implantation of a fertilized egg outside the uterus, representing a potentially life-threatening condition. The most common location is the fallopian tube, although other sites such as the cervix or cesarean scars are also possible. Despite diagnostic and therapeutic advances, disparities in access to care persist. The condition has significant physical, emotional, and reproductive consequences. Diagnosis has improved with transvaginal ultrasound and ẞ-hCG measurement, and treatment has evolved from open surgery to medical options like methotrexate.

    Case report: a 29-year-old woman presented with pelvic pain, metrorrhagia, and mild hemodynamic instability. Transvaginal ultrasound and ẞ-hCG levels confirmed a tubal ectopic pregnancy. Intramuscular methotrexate was administered, followed by clinical and hormonal monitoring. The patient showed favorable progression, with decreasing ẞ-hCG levels and complete resolution without complications. She received reproductive counseling and emotional support.

    Conclusions: methotrexate proved effective in an uncomplicated ectopic pregnancy. Proper patient selection, strict follow-up, and a comprehensive approach that includes emotional care are key to successful management. Evidence supports this conservative medical treatment as a safe and effective alternative.