Introduction: Piper auritum Kunth (anise sage) is one of the most traditionally used plants in Cuba for its anti-inflammatory, analgesic, and wound-healing properties. Objective: To determine the efficacy of topical application of anise sage leaves in patients with traumatic and infectious facial edema. Method: A cross-sectional, descriptive, observational study was conducted from January to April 2024. The sample consisted of 20 individuals of both sexes, hospitalized in the maxillofacial surgery service, who presented with traumatic and infectious facial edema. Results: Of the total number of patients examined, the 18-29 age group predominated, with males and white skin. Conclusions: A predominance of the 18-29 age group was found, with males predominating. The majority of patients treated with Piper auritum Kunth were Caucasian. The best results were found with 15-minute applications every 8 hours, achieving a reduction in edema across almost the entire area.
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