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Progresión del astigmatismo a largo plazo y su interacción con el equivalente esférico en niños chinos en edad escolar: un estudio de cohorte de base hospitalaria.

  • Zhuoer Qin [1] ; Qiaolan Zheng [1] ; Yuanyuan Liu [1] ; Ying Chen [1] ; Xinping Yu [2] ; Jie Chen [1] ; Dan Xu [1] ; Wuhe Chen [1]
    1. [1] National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China
    2. [2] Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, Guangdong, China
  • Localización: Journal of Optometry: peer-reviewed Journal of the Spanish General Council of Optometry, ISSN-e 1888-4296, Vol. 19, Nº. 2, 2026
  • Idioma: español
  • Títulos paralelos:
    • Long-term astigmatism progression and its interaction with spherical equivalent in Chinese school-age children: A hospital-based cohort study
  • Enlaces
  • Resumen
    • Purpose To characterize longitudinal astigmatism changes and their interaction with spherical equivalent (SE) progression in Chinese school-age children.

      Methods We retrospectively reviewed medical records of patients with long-term follow-up data from 2008 to 2022. Patients aged 6–10 years at initial visit and 16 years at last assessment, with a cylinder refraction of 0.75 D or greater, were selected. Astigmatism was analyzed in clinical notation and vector notation (J0, J45). Factors related to annual changes in astigmatism and SE and their interaction were analyzed.

      Results A total of 2946 patients (mean age 8.72 ± 1.21 years at initial visit) were followed up for 7.40 ± 1.23 years. In low astigmatism (≤1.50 D), cylinder power increased by 0.018 D/y with age, whereas in high astigmatism (≥3.00 D), it decreased by 0.048 D/y (p < 0.001). Oblique astigmatism (J45) increased by 0.008 D/y, and with-the-rule (WTR) astigmatism (J0) decreased by 0.005 D/y (p < 0.001). A more negative baseline SE at initial visit was associated with greater increase in astigmatism magnitude (β = -0.004, p < 0.001), and higher baseline astigmatism magnitude was associated with less SE progression (β = 0.047, p < 0.001).

      Conclusion In this large longitudinal cohort of Chinese school-age children, astigmatism progression exhibited a baseline-dependent pattern. Myopia was associated with a modest acceleration of astigmatism progression, whereas higher astigmatism conferred a slight protective effect against myopic shift. This study demonstrates these refractive interactions, though their clinical applicability is limited by small effect sizes.


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