Impact of microwave ablation on survival rates and recurrence in hepatic malignant tumors

• Jutian Shi ^[1] ; Yutian Jiang ^[2] ; Jinpeng Li ^[1] ; Hua Chen ^[1] ; Ning Cong ^[1]
  1. [1] Intervention Ward One, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, No. 440, Jiyan Road, Huaiyin District, Jinan 250000, Shandong Province, China
  2. [2] Department of Interventional, Yan Tai Yu Huangding Hospital, Yan Tai 264000, China
• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 27, Nº. 3, 2025, págs. 1131-1141
• Idioma: inglés
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• Resumen

  • Purpose This study aimed to evaluate the efcacy of percutaneous microwave ablation (MWA) for treating hepatic malignant tumors and to identify factors infuencing tumor recurrence post-treatment.

    Methods A total of 249 patients with hepatic malignant tumors treated at the Shandong Cancer Hospital and Institute were included, and 101 patients were analyzed. Disease-free and overall survival rates were assessed at 1, 2, and 3 years post-MWA. Correlations between tumor recurrence and factors such as Child–Pugh B classifcation and lesion count were examined, and a meta-analysis was conducted to identify independent risk factors for recurrence.

    Results The study found disease-free survival rates of 80.2%, 72.3%, and 70.3% at 1, 2, and 3 years post-MWA, with overall survival rates at 99%, 97%, and 96%. Signifcant correlations were observed between tumor recurrence, Child–Pugh B classifcation, and the number of lesions. Meta-analysis confrmed lesion count and Child–Pugh B classifcation as independent risk factors for recurrence following MWA treatment.

    Conclusion The study underscores the importance of considering Child–Pugh B classifcation and lesion count in predicting tumor recurrence after MWA for hepatic malignant tumors. These fndings ofer valuable insights for clinicians in decisionmaking and post-treatment monitoring.