A Delphi consensus on diagnosis, management, and treatment with allergen immunotherapy of polysensitized children in Spain: CAPP study, Part 1

• María Mesa del Castillo ^[1] ; Francisco J. Canals ^[2] ; Candela Ana Martínez Cañavate ^[7] ; Cristina Rivas Juesas ^[3] ; Helena Larramona Cabrera ^[8] ; Miguel Tortajada Girbés ^[9] ; José Manuel Lucas Moreno ^[10] ; Maria del Mar Folqué ^[4] ; Ana Morales Tirado ^[5] ; Ana I. Tabar ^[6]
  1. [1] Hospital de Móstoles

     Hospital de Móstoles

     Móstoles, España

     
  2. [2] Hospital General Universitario de Elche

     Hospital General Universitario de Elche

     Elche, España

     
  3. [3] Hospital de Sagunto

     Hospital de Sagunto

     Sagunto/Sagunt, España

     
  4. [4] Hospital Sant Joan de Deu

     Hospital Sant Joan de Deu

     Barcelona, España

     
  5. [5] Hospital Ramón y Cajal

     Hospital Ramón y Cajal

     Madrid, España

     
  6. [6] Hospital Universitario de Navarra

     Hospital Universitario de Navarra

     Pamplona, España

     
  7. [7] Unidad de Alergia Infantil, Hospital Materno Infantil Virgen de las Nieves de Granada, Spain
  8. [8] Servicio de Pediatria, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain
  9. [9] Sección de Neumología y Alergología Pediátrica, Hospital Universitario y Politécnico La Fe, Valencia, Spain
  10. [10] Sección Alergia Pediátrica, Servicio de Pediatría, Hospital Clínico Universitario Virgen Arrixaca. Murcia, Spain

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• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 53, Nº. 2, 2025, págs. 124-140
• Idioma: inglés
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  • Background:The study aimed to evaluate the level of agreement between specialists in pediatric allergology regarding the diagnosis and indications for pollen allergen immunother-apy (AIT) of polysensitized children in Spain.Materials and methods:A Delphi study was performed using an online survey designed by a committee of pediatric AIT experts: 46 and 44 panelists participated in rounds 1 and 2, respectively. In round 1, 204 statements on 8 dimensions were evaluated (Diagnosis; Therapeutic management; Pollens – Part I; Mites; Moulds; Animals; Hymenoptera venom; and Mixtures - Part II). A total of 148 statements were finally accepted after round 2. Panel members rated their level of agreement with assessments on a 9-point Likert scale based on acceptance by ≥ 66.7% of them.Results:According to the results, the polysensitization determination in allergic patients is confirmed by clinical history, skin prick test, total and specific IgE, and molecular diagnos-tics. Clinical assessments are recommended for the AIT effectiveness evaluation. Follow-ups