Sickle Cell Disease and Cardiovascular Damage: Understanding the connection and straregies for prevention

• García Salgado , Anelys García Salgado ^[2] ; Agramonte Llanes , Olga Margarita ^[1] ; Gámez Pérez , Anadely ^[3]
  1. [1] Universidad de Ciencias Médicas de la Habana

     Universidad de Ciencias Médicas de la Habana

     Cuba

     
  2. [2] Facultad de Ciencias Médicas de Artemisa, Hospital “Ivan Portuondo”. Artemisa, Cuba
  3. [3] Facultad de Ciencias Médicas de Artemisa, Hospital General Docente Comandante Pinares. Artemisa, Cuba

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• Localización: Health Leadership and Quality of Life, ISSN-e 3008-8488, Vol. 3, Nº. 0, 2024 (Ejemplar dedicado a: Health Leadership and Quality of Life)
• Idioma: inglés
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  • Introduction: Cardiovascular alterations contribute to the morbidity of adult patients with sickle cell disease, as a clinical expression of chronic organ damage. Sickle cell disease is a generic term assigned to a group of genetic disorders characterizedby a predominance of hemoglobin S(HBS) and clinically expressed in homozygous or doublé heterozygous patients. Development: Alterations in cardiac morphology and function were identified from the earliest cases of sickle cell disease. The prevalence of cardiac involvement in adult patients with sickle cell disease has been estimated to be as high as 82%. Conclusions: Patients with sickle cell disease exhibit a high prevalence of cardiovascular alterations, including the need for regular cardiovascular monitoring in this population.