Nutrient-Stimulating Hormone-Based Therapies for Obesity

• Cristancho, Cagney ^[2] ; Wook Kim, Dong ^[1] ; M. Apovian, Caroline ^[1]
  1. [1] Harvard Medical School

     Harvard Medical School

     City of Boston, Estados Unidos

     
  2. [2] Center for Weight Management and Wellness, Division of Endocrinology, Diabetes and Hypertension, Brigham & Women’s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 54, Nº. 1, 2025, págs. 103-119
• Idioma: inglés
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• Resumen

  • Achieving sustained weight loss requires a multifaceted, comprehensive strategy that starts by incorporating both dietary and behavioral interventions. Pharmacologic treatment serves as an option for patients who do not achieve desired results through lifestyle changes alone, or in whom a more substantial weight reduction is needed to reduce health comorbidities. NuSH-based therapies such as semaglutide or tirzepatide represent a new era of potent physiologic therapeutic options for effective