Journal of Pharmacology and Experimental Therapeutics

• 

  Año 2004, Vol. 309, Número 1

  • Brain Stimulation for Neurological and Psychiatric Disorders, Current Status and Future Direction

    J.-Y. Chang

    págs. 1-7

    

  • Estrogen Reduces Cardiac Injury and Expression of beta~1-Adrenoceptor upon Ischemic Insult in the Rat Heart

    K. W. L. Kam

    págs. 8-15

    

  • The Neuroprotective Effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a Novel alpha7 Ligand, Is Prevented through Angiotensin II Activation of a Tyrosine Phosphatase

    M. B. Marrero

    págs. 16-27

    

  • Transport of Pharmacologically Active Proline Derivatives by the Human Proton-Coupled Amino Acid Transporter hPAT1

    J. Kalbitz, L. Metzner, M. Brandsch

    págs. 28-35

    

  • Suppression of Acute Herpetic Pain-Related Responses by the kappa-Opioid Receptor Agonist (-)-17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-[N-methyl-3-trans-3-(3-furyl) Acrylamido] Morphinan Hydrochloride (TRK-820) in Mice

    I. Takasaki

    págs. 36-41

    

  • Role of Neuronal K~A~T~P Channels and Extraneuronal Monoamine Transporter on Norepinephrine Overflow in a Model of Myocardial Low Flow Ischemia

    C. Burgdorf, A. Dendorfer

    págs. 42-48

    

  • Studies of Abeta Pharmacodynamics in the Brain, Cerebrospinal Fluid, and Plasma in Young (Plaque-Free) Tg2576 Mice Using the gamma-Secretase Inhibitor N^2-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]- N^1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY-411575)

    T. A. Lanz, J. D. Hosley

    págs. 49-55

    

  • Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception

    S. Akerman

    págs. 56-63

    

  • NAD(P)H:Quinone Oxidoreductase-1-Dependent and -Independent Cytotoxicity of Potent Quinone Cdc25 Phosphatase Inhibitors

    B. I. Carr, H. Shen, Y. Han

    págs. 64-70

    

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin, an Exogenous Modulator of the 3'alpha Immunoglobulin Heavy Chain Enhancer in the CH12.LX Mouse Cell Line

    C. E. W. Sulentic

    págs. 71-78

    

  • Primaquine-Induced Hemolytic Anemia: Susceptibility of Normal versus Glutathione-Depleted Rat Erythrocytes to 5-Hydroxyprimaquine

    J. E. Oatis, Z. S. Bowman, D. J. Jollow, J. L. Whelan, D. C. McMillan

    págs. 79-85

    

  • Differential Effects of delta^9-Tetrahydrocannabinol and Methanandamide in CB1 Knockout and Wild-Type Mice

    C. Y. Baskfield

    págs. 86-91

    

  • Polyphenolic Antioxidants Mimic the Effects of 1,4-Dihydropyridines on Neurotensin Receptor Function in PC3 Cells

    R. E. Carraway

    págs. 92-101

    

  • Inverse Agonist Activity of Selected Ligands of the Cysteinyl-Leukotriene Receptor 1

    D. J. Dupre, C. Le Gouill

    págs. 102-108

    

  • Stimulation of Serotonin~2~C Receptors Blocks the Hyperactivation of Midbrain Dopamine Neurons Induced by Nicotine Administration

    M. Pierucci, V. Di Matteo

    págs. 109-118

    

  • Inhibitors of Tryptase as Mast Cell-Stabilizing Agents in the Human Airways: Effects of Tryptase and Other Agonists of Proteinase-Activated Receptor 2 on Histamine Release

    A. Aslam, Shaoheng He, M. D. A. Gaca

    págs. 119-126

    

  • Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque

    M. V. Fanucchi, R. M. Baldwin, W. T. Jewell

    págs. 127-136

    

  • Role of alpha-Adrenergic Receptors on the Effect of the beta-Adrenergic Receptor Ligands, CGP 12177, Bupranolol, and SR 59230A, on the Contraction of Rat Intrapulmonary Artery

    F. Pourageaud, V. Leblais

    págs. 137-145

    

  • Histogranin-Like Antinociceptive and Anti-Inflammatory Derivatives of o-Phenylenediamine and Benzimidazole

    H.-T. Le, I. B. Lemaire, A.-K. Gilbert

    págs. 146-155

    

  • Transport of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate by the Multidrug Resistance Proteins MRP1, MRP2, and MRP3

    S.-E. W. Huskey, X.-Y. Chu

    págs. 156-164

    

  • Characterization of the Contractile 5-Hydroxytryptamine Receptor in the Renal Artery of the Normotensive Rat

    S. W. Watts, J. M. Thompson

    págs. 165-172

    

  • delta-Opioid Agonists: Differential Efficacy and Potency of SNC80, Its 3-OH (SNC86), and 3-Desoxy (SNC162) Derivatives in Sprague-Dawley Rats

    E. M. Jutkiewicz

    págs. 173-181

    

  • Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]-beta-methoxyethoxyphenyl]s ulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia: In Vitro and in Vivo Studies

    G. E. Billman

    págs. 182-192

    

  • NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-Benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A New Selective Inhibitor of T-Type Calcium Channels

    T. M. Tagmose, B. M. Keyser, L. Huang

    págs. 193-199

    

  • The Cognition-Enhancer Nefiracetam Inhibits Both Necrosis and Apoptosis in Retinal Ischemic Models in Vitro and in Vivo

    M. Ueda, R. Fujita

    págs. 200-207

    

  • Imatinib-Mesylate Blocks Recombinant T-Type Calcium Channels Expressed in Human Embryonic Kidney-293 Cells by a Protein Tyrosine Kinase-Independent Mechanism

    V. Lariccia, A. Gaudino, M. Cataldi

    págs. 208-215

    

  • Ethanol Drinking and Deprivation Alter Dopaminergic and Serotonergic Function in the Nucleus Accumbens of Alcohol-Preferring Rats

    R. J. Thielen, E. A. Engleman

    págs. 216-225

    

  • Quantitative Evaluation of the Drug-Drug Interactions between Methotrexate and Nonsteroidal Anti-Inflammatory Drugs in the Renal Uptake Process Based on the Contribution of Organic Anion Transporters and Reduced Folate Carrier

    Y. Nozaki, H. Kusuhara

    págs. 226-234

    

  • Effects of SanOrg123781A, a Synthetic Hexadecasaccharide, in a Mouse Model of Electrically Induced Carotid Artery Injury: Synergism with the Antiplatelet Agent Clopidogrel

    I. Lechaire, C. Gauffeny, J. Lorrain

    págs. 235-240

    

  • Neutral and Anionic Liposome-Encapsulated Hemoglobin: Effect of Postinserted Poly(ethylene glycol)-distearoylphosphatidylethanolamine on Distribution and Circulation Kinetics

    V. D. Awasthi

    págs. 241-248