Journal of Pharmacology and Experimental Therapeutics

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  Año 2005, Vol. 315, Número 3

  • Nerve Growth Factor-Induced Migration of Endothelial Cells

    J.-P. Dolle

    págs. 1220-1305

    

  • Modulation of Agonist Binding to Human Dopamine Receptor Subtypes by L-Prolyl-L-leucyl-glycinamide and a Peptidomimetic Analog

    A. Mann, G. Pontoriero, W. Costain, V. Verma, J. M. Castellano

    págs. 1228-1236

    

  • Tolperisone-Type Drugs Inhibit Spinal Reflexes via Blockade of Voltage-Gated Sodium and Calcium Channels

    P. Kocsis, S. Farkas

    págs. 1237-1264

    

  • Role of O^6-Alkylguanine-DNA Alkyltransferase in Protecting against 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-Induced Long-Term Toxicities

    R. Nagasubramanian, R. J. Hansen

    págs. 1247-1402

    

  • Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells

    C. M. Smith, R. A. Graham

    págs. 1256-1287

    

  • Preclinical Pharmacology of FMPD [6-Fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: A Potential Novel Antipsychotic with Lower Histamine H~1 Receptor Affinity Than Olanzapine

    F. P. Bymaster, M. J. Benvenga, K. Rasmussen, D. O. Calligaro

    págs. 1265-1277

    

  • Intrinsic Efficacy of Antipsychotics at Human D~2, D~3, and D~4 Dopamine Receptors: Identification of the Clozapine Metabolite N-Desmethylclozapine as a D~2/D~3 Partial Agonist

    E. S. Burstein

    págs. 1278-1345

    

  • Differential Substrate and Inhibitory Activities of Ranitidine and Famotidine toward Human Organic Cation Transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)

    J. B. Pritchard, D. L. Bourdet

    pág. 1288

    

  • Cloning, Expression, and Functional Characterization of Human Cyclooxygenase-1 Splicing Variants: Evidence for Intron 1 Retention

    N. Qin, T. L. Reitz, S.-P. Zhang

    págs. 1298-1337

    

  • Mechanism of Vasopeptidase Inhibitor-Induced Plasma Extravasation: Comparison of Omapatrilat and the Novel Neutral Endopeptidase 24.11/Angiotensin-Converting Enzyme Inhibitor GW796406

    A. C. Sulpizio

    págs. 1306-1330

    

  • Modulation of Cytochrome c Oxidase-Va Is Possibly Involved in Metallothionein Protection from Doxorubicin Cardiotoxicity

    K. E. Merten

    págs. 1314-1411

    

  • Comparison of Intravenous Buprenorphine and Methadone Self-Administration by Recently Detoxified Heroin-Dependent Individuals

    S. D. Comer, M. A. Sullivan

    pág. 1320

    

  • Direct and Irreversible Inhibition of Cyclooxygenase-1 by Nitroaspirin (NCX 4016)

    T. Corazzi

    págs. 1331-1361

    

  • Pharmacological Characterization of Human and Murine Neuropeptide S Receptor Variants

    R. K. Reinscheid

    págs. 1338-1353

    

  • Unequal Neuroprotection Afforded by the Acetylcholinesterase Inhibitors Galantamine, Donepezil, and Rivastigmine in SH-SY5Y Neuroblastoma Cells: Role of Nicotinic Receptors

    E. Arias, Sonia Gallego Sandín

    págs. 1346-1367

    

  • Functional Domains of the Mouse beta~3-Adrenoceptor Associated with Differential G Protein Coupling

    D. S. Hutchinson, M. Sato

    pág. 1354

    

  • In Vivo Antiarrhythmic and Cardiac Electrophysiologic Effects of a Novel Diphenylphosphine Oxide I~K~u~r Blocker (2-Isopropyl-5-methylcyclohexyl) Diphenylphosphine Oxide

    G. L. Stump, A. A. Wallace

    págs. 1362-1385

    

  • Expression of the Third Intracellular Loop of the delta-Opioid Receptor Inhibits Signaling by Opioid Receptors and Other G Protein-Coupled Receptors

    Z. Georgoussi, E. Morou

    págs. 1368-1379

    

  • Orexin 1 Receptor Activation Attenuates Neurogenic Dural Vasodilation in an Animal Model of Trigeminovascular Nociception

    P. R. Holland

    pág. 1380

    

  • In Vitro Evidence That Carteolol Is a Nonconventional Partial Agonist of Guinea Pig Cardiac beta~1-Adrenoceptors: A Comparison with Xamoterol

    M. Floreani

    pág. 1386

    

  • Specific Inhibition of Hormone-Sensitive Lipase Improves Lipid Profile while Reducing Plasma Glucose

    D. B. Lowe, T. H. Claus

    pág. 1396

    

  • Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms

    C. Gaiddon, P. Jeannequin

    pág. 1403

    

  • Comments on "Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties"

    D. L. Simmons, N. V. Chandrasekharan

    págs. 1412-1414

    

  • Response to Comments on "Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties"

    J. A. Snipes, D. W. Busija, B. Kis

    págs. 1415-1416