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Resumen de Mexican consensus on cow’s milk protein allergy

Jaime Alfonso Ramírez Mayans, Karen Ignorosa Arellano, Erick Toro Monjaraz, Roberto Cervantes Bustamante, Marlene Alejandra Ruiz Castillo, Isabel Medina Vera, Ana Gabriela Ayala Germán, Dante Bacarreza Nogales, Lucía Casas Guzik, José Antonio Chávez Barrera, Sergio Díaz Madero, Laura Esther Flores Fong, Manuel Enrique Galaz Pantoja Méndez, Judith Gris Calvo, Rosa Elena Huerta Hernández, Ana Elena Limón Rojas, Héctor Macías Avilés, Carlos Méndez Nieto, J.A. Ortega Martell, C.I. Oyervides García, Rubén Peña Vélez, José Nicolás Reynés Manzur, María del Mar Sáez de Ocariz Gutiérrez, Gerardo Sagols Méndez, Martha Eugenia Uriquidi Rivera, Liliana Worona, Guillermo Hideo Wakida Kusunoki, Y. Vandenplas

  • Background: The aim of this study is to present the current views of a diverse group of experts on the diagnosis and treatment of Cow’s Milk Protein Allergy (CMPA) in children under 2 years of age in Mexico.

    Material and methods: The study, led by a scientific committee of five experts in CMPA, was divided into six phases, including a modified Delphi process. A total of 20 panelists, all of whom were pediatric specialists, participated in administering a comprehensive 38-item questionnaire. The questionnaire was divided into two blocks: Diagnosis and Treatment (20 items each).

    Results: Consensus was reached on all the proposed items, with an agreement rate of over 70% for each of them. As a result, a diagnostic and treatment algorithm was developed that emphasized the reduction of unnecessary diagnostic studies and encouraged breastfeeding whenever possible. In cases where breast milk is not available, appropriate use of hypoallergenic formulas was recommended. In addition, recommendations on treatment duration and gradual reintroduction of cow’s milk protein were provided.

    Conclusions: The recommendations endorsed by 20 Mexican pediatricians through this study are applicable to everyday clinical practice, thereby enhancing the diagnosis and treatment of children under 2 years of age with CMPA. This, in turn, will foster improved health outcomes and optimize the utilization of healthcare resources.


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