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Mexican consensus on cow’s milk protein allergy

  • Jaime Alfonso Ramírez Mayans [1] ; Karen Rubi Ignorosa Arellano [1] ; Erik Manuel Toro Monjaraz [1] ; Roberto Cervantes Bustamante [1] ; Marlene Alejandra Ruiz Castillo [6] ; Isabel de Jesús Medina Vera [1] ; Ana Gabriela Ayala Germán [7] ; Dante Vladimir Bacarreza Nogales [8] ; Lucía Casas Guzik [9] ; José Antonio Chávez Barrera [10] ; Sergio Díaz Madero [2] ; Laura Esther Flores Fong [3] ; Manuel Enrique Galaz Pantoja Méndez [11] ; Judith Ileana Gris Calvo [1] ; Rosa Elena Huerta Hernández [12] ; Ana Elena Limón Rojas [13] ; Héctor Macías Avilés [1] ; Carlos Méndez Nieto [14] ; José Antonio Ortega Martell [12] ; Carlos Iván Oyervides García [15] ; Rubén Peña Vélez [16] ; José Nicolás Reynés Manzur [1] ; María del Mar Saez de Ocariz Gutiérrez [1] ; Gerardo Sagols Méndez [17] ; Martha Eugenia Uriquidi Rivera [18] ; Liliana Worona Dibner [4] ; Guillermo Hideo Wakida Kusunoki [19] ; Yvan Vandenplas [5]
    1. [1] Instituto Nacional de Pediatria

      Instituto Nacional de Pediatria

      México

    2. [2] Hospital Español

      Hospital Español

      México

    3. [3] Hospital Civil de Guadalajara

      Hospital Civil de Guadalajara

      México

    4. [4] Hospital Infantil de México Federico Gómez

      Hospital Infantil de México Federico Gómez

      México

    5. [5] Vrije Universiteit Brussel

      Vrije Universiteit Brussel

      Arrondissement Brussel-Hoofdstad, Bélgica

    6. [6] Pediatric Gastroenterology, Hospital del Niño DIF, Hidalgo México
    7. [7] Pediatric Gastroenterology, Hospital General Agustín O Haran, Mérida, Yucatán, México
    8. [8] Pediatric Gastroenterology, Hospital General Zona 1 IMSS, Tijuana, México
    9. [9] Pediatric Gastroenterology, Hospital Infantil de Morelia Eva Sámano de López Mateos, Morelia, México
    10. [10] Pediatric Gastroenterology, Hospital General del Centro Médico Nacional La Raza, IMSS, Mexico City
    11. [11] Pediatric Gastroenterology, Hospital General Chiapas, Mexico
    12. [12] Clínica de Alergia Pediátrica, Pachuca, Hidalgo, Mexico
    13. [13] Pediatrics, Secretaría Clínica Facultad de Medicina, UNAM, Mexico City
    14. [14] Pediatric Gastroenterology, Hospital Infantil de Especialidades, Ciudad Juárez, Mexico
    15. [15] Pediatric Gastroenterology, Hospital del Niño Dr. Federico Gómez Santos, Saltillo, Coahuila, Mexico
    16. [16] Pediatric Gastroenterology, Hospital General de Puebla Dr. Eduardo Vázquez N., Puebla, Mexico
    17. [17] Pediatric Gastroenterology, Clínica de Mérida, SA de CV, Merida, Mexico
    18. [18] Pediatric Gastroenterology, ISSSTE Hospital Regional Monterrey, Nuevo León, Mexico
    19. [19] Pediatric Allergy and Immunology, Hospital Central Sur de Alta Especialidad de Petróleos Mexicanos, Mexico City
  • Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 52, Nº. 1, 2024, págs. 24-37
  • Idioma: inglés
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  • Resumen
    • Background: The aim of this study is to present the current views of a diverse group of experts on the diagnosis and treatment of Cow’s Milk Protein Allergy (CMPA) in children under 2 years of age in Mexico.

      Material and methods: The study, led by a scientific committee of five experts in CMPA, was divided into six phases, including a modified Delphi process. A total of 20 panelists, all of whom were pediatric specialists, participated in administering a comprehensive 38-item questionnaire. The questionnaire was divided into two blocks: Diagnosis and Treatment (20 items each).

      Results: Consensus was reached on all the proposed items, with an agreement rate of over 70% for each of them. As a result, a diagnostic and treatment algorithm was developed that emphasized the reduction of unnecessary diagnostic studies and encouraged breastfeeding whenever possible. In cases where breast milk is not available, appropriate use of hypoallergenic formulas was recommended. In addition, recommendations on treatment duration and gradual reintroduction of cow’s milk protein were provided.

      Conclusions: The recommendations endorsed by 20 Mexican pediatricians through this study are applicable to everyday clinical practice, thereby enhancing the diagnosis and treatment of children under 2 years of age with CMPA. This, in turn, will foster improved health outcomes and optimize the utilization of healthcare resources.


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