Chapter One - A Personal Essay: My Experiences in the Pharmaceutical Industry
págs. 3-9
Chapter Two - Adventures in Medicinal Chemistry: A Career in Drug Discovery
págs. 11-23
Chapter Three - Natural and Synthetic Neuroactive Steroid Modulators of GABAA and NMDA Receptors
Gabriel Martinez-Botella, Michael A. Ackley, Francesco G. Salituro, James J. Doherty
págs. 27-42
Chapter Four - Development of LRRK2 Kinase Inhibitors for Parkinson's Disease
Paul Galatsis, Jaclyn Henderson, Bethany L. Kormos, Warren D. Hirst
págs. 43-58
págs. 59-73
págs. 77-86
págs. 87-99
págs. 101-113
págs. 117-133
Chapter Ten - H4 Receptor Antagonists and Their Potential Therapeutic Applications
David D. Burns, Niu Shin, Ravi Jalluri, Wenqing Yao, Peggy Scherle
págs. 135-149
págs. 151-164
Chapter Twelve - p53–MDM2 and MDMX Antagonists
Constantinos Neochoritis, Natalia Estrada, Kareem Khoury, Alexander Dömling
págs. 167-187
págs. 189-206
Chapter Fourteen - Advancement of Cell Wall Inhibitors in Mycobacterium tuberculosis
Pravin S. Shirude, Monalisa Chatterji, Shridhar Narayanan, Pravin S. Iyer
págs. 209-220
págs. 221-247
págs. 249-266
págs. 269-284
págs. 285-300
Chapter Nineteen - Mer Receptor Tyrosine Kinase: Therapeutic Opportunities in Oncology, Virology, and Cardiovascular Indications
págs. 301-314
págs. 317-330
págs. 331-345
págs. 347-359
Chapter Twenty-Three - Case History: ForxigaTM (Dapagliflozin), a Potent Selective SGLT2 Inhibitor for Treatment of Diabetes
págs. 363-382
Chapter Twenty-Four - Case History: Kalydeco® (VX-770, Ivacaftor), a CFTR Potentiator for the Treatment of Patients with Cystic Fibrosis and the G551D-CFTR Mutation
Sabine Hadida, Fredrick Van Goor, Kirk Dinehart, Adam R. Looker, Peter Mueller, Peter D.J. Grootenhuis
págs. 383-398
Chapter Twenty-Five - Case History: Xeljanz™ (Tofacitinib Citrate), a First-in-Class Janus Kinase Inhibitor for the Treatment of Rheumatoid Arthritis
Mark E. Flanagan, Matthew F. Brown, Chakrapani Subramanyam, Michael J. Munchhof
págs. 399-416
págs. 417-436
Chapter Twenty-Seven - To Market, To Market—2013
Joanne Bronson, Amelia Black, Murali Dhar, Bruce Ellsworth, J. Robert Merritt
págs. 437-508
págs. 509-517
págs. 519-542
págs. 543-568
© 2001-2024 Fundación Dialnet · Todos los derechos reservados