Publication: La enfermedad del ojo seco en pacientes con y sin fibromialgia. Estudio comparativo
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2021-07-19
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Universidad Complutense de Madrid
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Abstract
La enfermedad del ojo seco (EOS) es una de las afecciones oftalmológicas más presentes y relevantes en la población, tanto por sus repercusiones médicas como económicas. Se estima que entre el 5 y 50% de la misma la padecen (75%si consideramos los pacientes asintomáticos pero que presentan signos), siendo más frecuente en hispanos y asiáticos. Afecta fundamentalmente a las mujeres y se vea gravada por la edad. En el último informe de la Tear Film & Ocular Surface Society (TFOS), el Dry Eye Workshop (DEWS) II de 2017, se define como “una enfermedad multifactorial de la superficie ocular, que se caracteriza por una pérdida de la homeostasis de la película lagrimal y que va acompañada de síntomas oculares, en laque la inestabilidad e hiperosmolaridad de la superficie ocular, la inflamación y daño dela superficie ocular, y las anomalías neurosensoriales desempeñan papeles etiológicos”. Aunque de forma tradicional se ha clasificado como EOS tipo evaporativo, cuya causa más frecuente es la disfunción de las glándulas de Meibomio (DGM), y acuodeficiente; en el último DEWS se establece una clasificación mixta, con predominio de un tipo u otro. El padecimiento de esta enfermedad de carácter crónico implica una afectación importante de la calidad de vida, tanto por la alteración de la visión, como por las consecuencias físicas y psicológicas del dolor y síntomas con que se manifiesta, repercutiendo a su vez en la productividad de las personas...
Dry eye disease (DED) is one of the most common and relevant ophthalmological conditions in the population, due both to its clinical and economic consequences. It is estimated that 5 to 50 percent of the population is affected (75% if we consider asymptomatic patients who present signs), being more frequent in Hispanics and Asians. It mainly affects women and is aggravated by age. In the latest Tear Film & Ocular Surface Society (TFOS) report, the 2017 Dry Eye Workshop (DEWS II), it is defined as “a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear filmin stability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles”. Although traditionally it has been classified as evaporative dry eye (the most frequent cause is the Meibomian glands dysfunction [MGD]) and aqueous‐deficient dry eye, the latest DEWS has established a mixed classification, with the predominance of one type or another. The suffering of this chronic disease implies a significant impairment of the quality of life, due to both visual disturbances as well as the physical and psychological consequences of the pain. Therefore, people’s work productivity decreases...
Dry eye disease (DED) is one of the most common and relevant ophthalmological conditions in the population, due both to its clinical and economic consequences. It is estimated that 5 to 50 percent of the population is affected (75% if we consider asymptomatic patients who present signs), being more frequent in Hispanics and Asians. It mainly affects women and is aggravated by age. In the latest Tear Film & Ocular Surface Society (TFOS) report, the 2017 Dry Eye Workshop (DEWS II), it is defined as “a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear filmin stability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles”. Although traditionally it has been classified as evaporative dry eye (the most frequent cause is the Meibomian glands dysfunction [MGD]) and aqueous‐deficient dry eye, the latest DEWS has established a mixed classification, with the predominance of one type or another. The suffering of this chronic disease implies a significant impairment of the quality of life, due to both visual disturbances as well as the physical and psychological consequences of the pain. Therefore, people’s work productivity decreases...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Inmunología, Oftalmología y Otorrinolaringología, leída el 27/11/2020