Publication: Posfuncionalización de colorantes BODIPY para aplicaciones fotónicas y biofotónicas
Loading...
Official URL
Full text at PDC
Publication Date
2021-06-02
Authors
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Complutense de Madrid
Citations
Exportar
Abstract
El objetivo de la presente Tesis, titulada "Posfuncionalización de colorantes BODIPY para aplicaciones fotónicas y biofotónicas" es el diseño, síntesis y estudio de nuevos fluoróforos orgánicos con el fin de proporcionar soluciones químicas para el rápido desarrollo de sondas fluorescentes para aplicaciones avanzadas en biología y tecnología. Desde el punto de vista de la química orgánica, hemos basado nuestra investigación en el desarrollo de métodos fáciles, versátiles y eficientes para la posfuncionalización química del fluoróforo BODIPY (4-bora-3-a,4a-diaza-s-indaceno). El manuscrito de la tesis se puede dividir en dos partes principales. La primera parte (Capítulos 2-4) describe una estrategia general y práctica para la incorporación directa en un solo paso de α- o β-hidroxiácidos en el átomo de boro de los colorantes F-BODIPY para proporcionar los derivados O-BODIPY correspondientes...
The objective of the present Thesis, entitled “Postfunctionalization of BODIPY dyes for photonic and biophotonic applications” is the design, synthesis and study of novel organic fluorophores to provide chemical solutions for the fast development of fluorescent probes for advanced applications in biology and technology. From the organic chemistry point of view, we have based our research on the development of facile, versatile and efficient methods for the chemical postfunctionalization of the BODIPY (4-bora-3-a,4a-diaza-s-indacene) fluorophore.The thesis manuscript can be divided into two main parts. The first part (Chapters 2-4) describes a general and practical strategy for the direct one-step incorporation of α- or β-hydroxy acids onto the boron atom of F-BODIPYs dyes to afford the corresponding O-BODIPY derivatives...
The objective of the present Thesis, entitled “Postfunctionalization of BODIPY dyes for photonic and biophotonic applications” is the design, synthesis and study of novel organic fluorophores to provide chemical solutions for the fast development of fluorescent probes for advanced applications in biology and technology. From the organic chemistry point of view, we have based our research on the development of facile, versatile and efficient methods for the chemical postfunctionalization of the BODIPY (4-bora-3-a,4a-diaza-s-indacene) fluorophore.The thesis manuscript can be divided into two main parts. The first part (Chapters 2-4) describes a general and practical strategy for the direct one-step incorporation of α- or β-hydroxy acids onto the boron atom of F-BODIPYs dyes to afford the corresponding O-BODIPY derivatives...
Description
Tesis inédita de la Universidad Complutense de Madrid, Facultad de Farmacia, leída el 27-10-2020