Publication: Optimización de las técnicas convectivas en el tratamiento de los pacientes con enfermedad renal crónica en hemodiálisis
Loading...
Files
Official URL
Full text at PDC
Publication Date
2020-02-18
Authors
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Complutense de Madrid
Citations
Exportar
Abstract
La elevada morbimortalidad de los pacientes en diálisis se ha relacionado con la retención de una gran variedad de toxinas urémicas. La hemodiafiltración on-line (HDF-OL) post-dilución con altos volúmenes de sustitución se considera la técnica más eficiente en la eliminación de solutos y se asocia a una mejoría en la supervivencia respecto a la hemodiálisis (HD) convencional. Cada vez existe más evidencia de que los beneficios de la HDF-OL se relacionan directamente con la cantidad de transporte convectivo, probablemente por una mayor depuración de toxinas urémicas, por lo que se han propuesto unos objetivos mínimos de volumen de sustitución para conseguir una reducción significativa en la mortalidad...
The elevated mortality rates of patients on dialysis have been related to the retention of a wide variety of uremic toxins. Post-dilution online hemodiafiltration (OL-HDF) with high substitution volumes is recognized as the most efficient therapy for solute elimination, and it has been associated with improved patient survival compared to conventional hemodialysis (HD). There is increasing evidence that the benefits of OL-HDF are directly related to the amount of convective transport, probably due to a higher removal of uremic toxins, and therefore a minimum goal of replacement volume have been proposed to achieve a significant reduction in mortality...
The elevated mortality rates of patients on dialysis have been related to the retention of a wide variety of uremic toxins. Post-dilution online hemodiafiltration (OL-HDF) with high substitution volumes is recognized as the most efficient therapy for solute elimination, and it has been associated with improved patient survival compared to conventional hemodialysis (HD). There is increasing evidence that the benefits of OL-HDF are directly related to the amount of convective transport, probably due to a higher removal of uremic toxins, and therefore a minimum goal of replacement volume have been proposed to achieve a significant reduction in mortality...
Description
Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 21-11-2019