NombreLópez Martín, Sergio
DepartamentoBiología Celular
Área de conocimientoBiología Celular
Categoría profesionalProfesor Contratado Doctor
Correo electrónicoSolicitar
         
  • Nº publicaciones

    35

  • Nº visitas

    3021

  • Nº descargas

    7449


 

Trabajo Fin de Grado
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Arteriosclerosis.

Matador Romero, José Miguel; López Martín, Sergio (2023)
Este trabajo se centra en el tema de la arterioesclerosis, abordando distintos aspectos relevantes de esta enfermedad. ...
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Impact of Gastrointestinal Digestion In Vitro Procedure on the Characterization and Cytotoxicity of Reduced Graphene Oxide

Cebadero Domínguez, Óscar; Díez-Quijada Jiménez, Leticia; López Martín, Sergio; Sánchez Ballester, Soraya; Puerto Rodríguez, María; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The growing interest in graphene derivatives is a result of their variety of applications in many fields. Due to their ...
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Immediate-release Niacin and a Monounsaturated Fatty Acid-rich Meal on Postprandial Inflammation and Monocyte Characteristics in Men with Metabolic Syndrome

Montserrat de la Paz, Sergio; Naranjo, María del Carmen; López Martín, Sergio; Millán Linares, María del Carmen; Rivas Domínguez, Antonio; Jaramillo Carmona, Sara María; Abia, Rocío; Muriana, Francisco J.G.; Bermúdez Pulgarín, Beatriz (Elsevier, 2023)
Background & aim: When considered separately, long-term immediate-release niacin and fatty meals enriched in monounsaturated ...
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Toxic Effects of the Cylindrospermopsin and Chlorpyrifos Combination on the Differentiated SH-SY5Y Human Neuroblastoma Cell Line

Hinojosa, María G.; Gutiérrez-Praena, Daniel; López Martín, Sergio; Prieto Ortega, Ana Isabel; Moreno Onorato, Francisco Javier; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2023)
Due to climate change and anthropogenic activities, the levels of pollution of aquatic and terrestrial environments have ...
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Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway

Manzano López, Javier; Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Pérez Linero, Ana María; Cordones Romero, Antonio; Aguilera Romero, María Auxiliadora; Lucena Hernández, Rafael; López Martín, Sergio; Muñiz Guinea, Manuel (Public Library of Science, 2022)
Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and ...
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CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets

Medrano, Mayte; Lemus Conejo, Ana; López Martín, Sergio; Millán-Linares, María del Carmen; Rosillo Ramírez, María de los Ángeles; Muñiz Guinea, Manuel; Calderón Ruíz, Rocío; Pérez Simón, José Antonio; Abia González, María del Rocío (Elsevier, 2022)
Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ...
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New evidence for dietary fatty acids in the neutrophil traffic between the bone marrow and the peripheral blood

Ortega Gómez, Almudena; López Martín, Sergio; Varela Pérez, Lourdes María; Jaramillo Carmona, Sara; García Muriana, Francisco José; Abia González, María del Rocío (Elsevier, 2022)
Chronic administration of a high-fat diet in mice has been established to influence the generation and trafficking of ...
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Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites

Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Ikeda, Atsuko; Araki, Misako; Okazaki, Kouta; Nakano, Miyako; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Waga, Miho; Nakano, Akihiko; Kurokawa, Kazuo; Muñiz Guinea, Manuel; Funato, Kouichi (Elsevier, 2022)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export ...
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Determination of the lipid composition of the GPI anchor

Aguilera Romero, María Auxiliadora; Sabido Bozo, Susana; López Martín, Sergio; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Pérez Linero, Ana María; Riezman, Isabelle; Riezman, Howard; Muñiz Guinea, Manuel (PLOS, 2021)
In eukaryotic cells, a subset of cell surface proteins is attached by the glycolipid glycosylphosphatidylinositol (GPI) ...
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MUFAs in High-Fat Diets Protect against Obesity-Induced Bias of Hematopoietic Cell Lineages

Lemus Conejo, Ana; Medrano, Mayte; López Martín, Sergio; Millán-Linares, María del Carmen; Rosillo Ramírez, María de los Ángeles; Pérez Simón, José Antonio; Muriana, Francisco J. G.; Abia González, María del Rocío (Wiley, 2021)
Scope: The role of dietary fatty acids in the generation of bone marrow (BM) immune cells and their trafficking to ...
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Structural analysis of the GPI glycan

Nakano, Miyako; Sabido Bozo, Susana; Okazaki, Kouta; Aguilera Romero, María Auxiliadora; Rodríguez Gallardo, Sofía; Cortés Gómez, Alejandro; López Martín, Sergio; Ikeda, Atsuko; Funato, Kouichi; Muñiz Guinea, Manuel (PLOS, 2021)
Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes ...
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Assay for dual cargo sorting into endoplasmic reticulum exit sites imaged by 3D Super-resolution Confocal Live Imaging Microscopy (SCLIM)

Rodríguez Gallardo, Sofía; Kurokawa, Kazuo; Cortés Gómez, Alejandro; Pérez Linero, Ana María; Aguilera Romero, María Auxiliadora; López Martín, Sergio; Nakano, Akihiko (Public Library of Science, 2021)
Understanding how in eukaryotic cells thousands of proteins are sorted from each other through the secretory pathway and ...
Artículo
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The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection

Sabido Bozo, Susana; Pérez Linero, Ana María; Manzano López, Javier; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Wellinger, Ralf Erik; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ...
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An opinion on the regulation of bone marrow adipose tissue by dietary fatty acids

López Martín, Sergio; Lemus Conejo, Ana; Rosillo Ramírez, María de los Ángeles; García Muriana, Francisco José; Abia González, María del Rocío (CSIC, 2020)
Obesity has a significant impact on predisposition to various diseases and also affects the viabil­ity and choice of ...
Artículo
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Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites

Rodríguez Gallardo, Sofía; Kurokawa, Kazuo; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Ikeda, Atsuko; Zoni, Valeria; Aguilera Romero, María Auxiliadora; Pérez Linero, Ana María; López Martín, Sergio; Muñiz Guinea, Manuel (American Association for the Advancement of Science, 2020)
Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition ...
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Changes in Lipoinflammation Markers in People with Obesity after a Concurrent Training Program: A Comparison between Men and Women

González Jurado, José Antonio; Suárez Carmona, Walter; López Martín, Sergio; Sánchez Oliver, Antonio Jesús (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Obesity is related to low-grade systemic inflammation. This state of inflammation is characterized by the alteration in ...
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Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum

López Martín, Sergio; Pérez Linero, Ana María; Manzano López, Javier; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Goder, Veit; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic ...
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Endoplasmic Reticulum Export of GPI-Anchored Proteins

López Martín, Sergio; Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Muñiz Guinea, Manuel (MDPI, 2019)
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat ...
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Long-Term Evaluation of Mesophilic Semi-Continuous Anaerobic Digestion of Olive Mill Solid Waste Pretreated with Steam-Explosion

Serrano, Antonio; González Fermoso, Fernando; Alonso-Fariñas, Bernabé; Rodríguez Gutiérrez, Guillermo; López Martín, Sergio; Fernández Bolaños, Juan; Borja Padilla, Rafael (MDPI, 2019)
Steam-explosion is a promising technology for recovering phenolic compounds from olive mill solid waste (OMSW) due to its ...
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A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge

López Martín, Sergio; Bermúdez Pulgarín, Beatriz; Montserrat de la Paz, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous ...
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In Vitro Toxicity of Asparagus Saponins in Distinct Multidrug-Resistant Colon Cancer Cells

Jaramillo Carmona, Sara; Guillén Bejarano, Rafael; Jiménez Araujo, Ana José; Rodríguez Arcos, Rocío; López Martín, Sergio (Wiley-Blackwell, 2018)
Colorectal cancer is the third most common cancer in the world. Many efforts have focused on finding natural molecules ...
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Effects of immediate‐release niacin and dietary fatty acids on acute insulin and lipid status in individuals with metabolic syndrome

Montserrat de la Paz, Sergio; López Martín, Sergio; Bermúdez Pulgarín, Beatriz; Guerrero Montávez, Juan Miguel; Alba González, María Rocío; García Muriana, Francisco José (John Wiley & Sons, 2018)
BACKGROUND The nature of dietary fats profoundly affects postprandial hypertriglyceridemia and glucose homeostasis. Niacin ...
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Dietary fatty acids and lipoproteins on progression of age-related macular degeneration

Montserrat de la Paz, Sergio; Naranjo Gutiérrez, María del Carmen; Bermúdez Pulgarín, Beatriz; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (CSIC, 2017)
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have ...
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Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells

López Martín, Sergio; Montserrat de la Paz, Sergio; Lucas Rodríguez, Ricardo; Bermúdez Pulgarín, Beatriz; Abia González, María del Rocío; Morales, Juan C.; García Muriana, Francisco José (Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ...
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Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells

García Muriana, Francisco José; Montserrat de la Paz, Sergio; Lucas Rodríguez, Ricardo; Bermúdez Pulgarín, Beatriz; Jaramillo Carmona, Sara; Morales, Juan C.; Abia González, María del Rocío; López Martín, Sergio (Royal Society of Chemistry, 2017)
Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass ...
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Dietary fatty acids on aortic root calcification in mice with metabolic syndrome

Naranjo, María C.; Bermúdez Pulgarín, Beatriz; García, Indara; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José; Montserrat de la Paz, Sergio (Royal Society of Chemistry, 2017)
Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. ...
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Exogenous fatty acids and niacin on acute prostaglandin D-2 production in human myeloid cells

Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; López Martín, Sergio; Naranjo, Maria C.; Romero, Yolanda; Bando Hidalgo, María J.; Abia González, María del Rocío; Muriana, Francisco J. G. (Elsevier, 2017)
Niacin activates HCA2 receptor that results in the release of PGD2. However, little is known on PGD2-producing cells and ...
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Saponin Profile of Wild Asparagus Species

Jaramillo Carmona, Sara; Rodríguez Arcos, Rocío; Jiménez Araujo, Ana José; López Martín, Sergio; Gil, Juan; Moreno, Roberto; Guillén Bejarano, Rafael (Wiley, 2017)
The aim of this work was to study the saponin profiles from spears of different wild asparagus species inthe context of ...
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The effects of exogenous fatty acids and niacin on human monocyte-macrophage plasticity

Montserrat de la Paz, Sergio; Rodríguez, Dolores; Cardelo, Magdalena P.; Naranjo, María C.; Bermúdez Pulgarín, Beatriz; Abia González, María del Rocío; García Muriana, Francisco José; López Martín, Sergio (Wiley-Blackwell, 2017)
Scope: Macrophage plasticity allows adapting to different environments, having a dual activity in inflammatory-related ...
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Niacin and olive oil promote skewing to the M2 phenotype in bone marrow-derived macrophages of mice with metabolic syndrome

Montserrat de la Paz, Sergio; Naranjo, Maria C.; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José; Bermúdez Pulgarín, Beatriz (Royal Society of Chemistry, 2016)
Metabolic syndrome (MetS) is associated with obesity, dyslipemia, type 2 diabetes and chronic low-grade inflammation. The ...
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Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome

Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; Cardelo, Magdalena P.; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in ...
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Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome

Montserrat de la Paz, Sergio; Naranjo, Maria C.; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José; Bermúdez Pulgarín, Beatriz (Elsevier, 2016)
We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated ...
Patente. Invención
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Composición emulsionada de grasa saturada en agua, su preparación y utilización para la evaluación de la tolerancia a los triglicéridos

Bermúdez Pulgarín, Beatriz; Pedroche Jiménez, Justo Javier; Varela Pérez, Lourdes María; Ortega Gómez, Almudena; López Martín, Sergio; Millán Rodríguez, Francisco; Abia González, María del Rocío; García Muriana, Francisco José; Carrera Sánchez, Cecilio; Rodríguez Patino, Juan Miguel (Oficina Española de Patentes y Marcas (OEPM), 2015)
Composición emulsionada de grasa saturada en agua, su preparación y utilización para la evaluación de la tolerancia a los ...
Tesis Doctoral
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Estudio de la respuesta postprandial de células vasculares y su implicación en la Aterosclerosis

Varela Pérez, Lourdes María; Abia González, María del Rocío; García Muriana, Francisco José; López Martín, Sergio (2012)
HIPÓTESIS La hipótesis de esta tesis supone que durante el metabolismo postprandial de las grasas de la dieta se generan ...
Tesis Doctoral
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Grasa saturada y monoinsaturada sobre factores de riesgo cardiovascular: Papel regulador de las lipoproteínas postprandiales ricas en triglicéridos en la dinámica de células pre-vasculares y vasculares

López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (2009)
El objetivo general de esta Tesis es comparar el efecto de tres tipos de comidas, una de ellas enriquecida con ácidos ...