Resumen de COPD and lung cancer: underdiagnosis and clinical characterization
Both COPD and LC share some common features, such as their high mortality and common risk factors as tobacco history, genetic background, environmental exposure and similar underlying pathogenic mechanisms. The aim of this project is to establish COPD prevalence, as well as its underdiagnosis in LC patients, and to analyze their clinical profile, comparing it with a control group of patients with COPD and no LC, evaluating different phenotypes and looking for biomarkers with potential at early diagnosis of LC or even with therapeutic and prognostic implications in this subset of patients. This work contains four different studies: a systematic review, a prospective cohort study based on patients with LC with/without COPD, and two case-control study with subjects with COPD with/without LC.
