Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile

• Carolina Coria ^[1] ; Aurora Cabello ^[1] ; Enzo Tassara ^[1] ; Eduardo López ^[1] ; Hugo Rosales ^[1] ; Marcelo Pérez ^[1] ; Claudia Zavala ^[1] ; Patricio Muñoz ^[1] ; Gabriel Orellana ^[2] ; María Isabel lnostroza ^[2] ; Lorena Contreras ^[2] ; Lilian Kirsten ^[1]
  1. [1] Universidad Católica de la Santísima Concepción

     Universidad Católica de la Santísima Concepción

     Comuna de Concepción, Chile

     
  2. [2] Hospital Clínico Herminda Martín Consultorio Adosado de Especialidades
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 137, Nº. 8, 2009, págs. 1037-1044
• Idioma: español
• Títulos paralelos:
  • Long term consequences among children exposed to lead poisoning
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• Resumen

  • Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 fig/dl, compared with those that had a lead level below 43 fig/dl (86.7±7.3 and 93±11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects aged ¡ess than six years at the moment of lead exposure had a lower IQ when assessed ten years later.