Fibrosis retroperitoneal asociada a uso crónico de ergotamina. Tratamiento con colchicina y esteroides: Caso clínico

• Jorge Vega ^[1] ; Helmuth Goecke ^[1] ; Mario Santamarina ^[2]
  1. [1] Hospital Naval A. Nef Sección de Nefrología Servicio de Medicina Interna
  2. [2] Hospital Naval A. Nef Servicio de Radiología
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 139, Nº. 4, 2011, págs. 489-494
• Idioma: español
• Títulos paralelos:
  • Retroperitoneal fibrosis associated with chronic use of ergotamine: Report of one case
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• Resumen

  • Retroperitoneal fibrosis (RPF) associated with chronic use of ergotamine is a very rare disorder. We report a 45-year-old woman who presented with a RPf after using, almost daily for 23 years, ergotamine tartrate for migraine relief. FRP presented as a chronicinflammatory state, anemia, abdominal and lumbosacral pain and a hypogastric mass. A CT-Scan showed a periaortic mass and left hydronephrosis. A percutaneous biopsy was obtained and the patient was subjected to a surgical ureterolysis and tissue resection. The biopsy confirmed the presence of RPf. Due to persistent symptoms and increase in the volume of periaortic tissue, treatment with colchicine 1 mg/day and defazacort 30 mg/day was started, resulting in a rapid di-sappearance of symptoms, disappearance ofinflammation and a significant reduction in the volume of the periaortic tissue. The patient remains in complete remission after 29 months of follow up.