Manifestaciones cutáneas de amiloidosis sistémica como clave diagnóstica: Caso clínico

• Félix Fich S ^[1] ; Marco Chahuán Y ^[2] ; Mª Magdalena Farías N ^[1] ; Consuelo Cárdenas D ^[1] ; Álvaro Abarzúa A ^[1] ; Gabriela Araya C ^[1] ; Sergio González B ^[1]
  1. [1] Pontificia Universidad Católica de Chile

     Pontificia Universidad Católica de Chile

     Santiago, Chile

     
  2. [2] Universidad de Chile/Hospital San Borja-Arriarán Facultad de Medicina Servicio de Medicina
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 140, Nº. 4, 2012, págs. 499-502
• Idioma: español
• Títulos paralelos:
  • AA amyloidosis with cutaneous manifestations: Report of one case
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• Resumen

  • Background: Systemic amyloidosis is a rare disease that can affect any organ. Its clinical manifestations are varied and nonspecific. The skin involvement of this disease is common and can be easily recognized on physical examination. We report a 57-year-old male presenting with a two years history of malaise, dyspnea and myalgias. On physical examination, ungueal dystrophy, orange pigmentation of eyelids with periocular petechiae and mild macroglossia were observed. Incisional biopsies of the eyelids, cheeks and hands were obtained. The pathological study demonstrated amyloid deposits. Since protein electrophoresis was normal, the diagnosis of AA amyloidosis was postulated.