El sedentarismo se asocia a un incremento de factores de riesgo cardiovascular y metabólicos independiente de los niveles de actividad física

• Ana María Leiva ^[1] ; María Adela Martínez ^[1] ; Carlos Cristi-Montero ^[2] ; Carlos Salas ^[3] ; Rodrigo Ramírez-Campillo ^[4] ; Ximena Díaz Martínez ^[5] ; Nicolás Aguilar-Farías ^[6] ; Carlos Celis-Morales ^[7]
  1. [1] Universidad Austral de Chile

     Universidad Austral de Chile

     Valdivia, Chile

     
  2. [2] Pontificia Universidad Católica de Valparaíso

     Pontificia Universidad Católica de Valparaíso

     Valparaíso, Chile

     
  3. [3] Universidad de Concepción

     Universidad de Concepción

     Comuna de Concepción, Chile

     
  4. [4] Universidad de Los Lagos

     Universidad de Los Lagos

     Osorno, Chile

     
  5. [5] Universidad del Biobío Grupo de Investigación Calidad de Vida y Estilos de Vida Saludable
  6. [6] Universidad de Temuco Departamento de Educación Física, Deportes y Recreación
  7. [7] University of Newcastle Institute of Cellular Medicine Human Nutrition Research Centre

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 145, Nº. 4, 2017, págs. 458-467
• Idioma: español
• Títulos paralelos:
  • Sedentary lifestyle is associated with metabolic and cardiovascular risk factors independent of physical activity
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• Resumen

  • Background: Sedentary behavior is a main risk factor for cardiovascular disease and mortality. Aim: To investigate the association between sedentary behavior and metabolic and cardiovascular risk factors. Material and Methods: We assessed 322 participants aged between 18 to 65 years. Physical activity and sedentary behavior were measured with accelerometers (Actigraph®). Body mass index (BMI), waist circumference, percentage of body fat, diet and blood markers (glucose, lipid profile, insulin and HOMA-IR) were measured with standardized protocols. Results: Thirty four percent of participants were physically inactive and spent on average 8.7 h/day on sedentary activities. Per one hour increase in sedentary behavior there were significant adverse changes in glucose (4.79 mg/dl), insulin (2.73 pmol/l), HOMA-IR (0.75), BMI (0.69 kg/m²), waist circumference (1.95 cm), fat mass (1.03%), total cholesterol (9.73 mg/dl), HDL-cholesterol (-3.50 mg/dl), LDL-cholesterol (10.7 mg/dl) and triglycerides (12.4 mg/dl). These findings were independent of main confounding factors including total physical activity, dietary factors, BMI and socio-demographics. Conclusions: The detrimental effect of sedentary behaviors on cardiometabolic and obesity-related traits is independent of physical activity levels. Therefore, reducing sedentary time should be targeted in the population apart from increasing their physical activity levels.