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Synthesis and structural characterization of n-benzoyl-tryptamine and its new analogue n-salicyloyltryptamine, a potential anticonvulsant agent

    1. [1] Universidade Federal da Paraíba

      Universidade Federal da Paraíba

      Brasil

  • Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 51, Nº. 2, 2006, págs. 919-922
  • Idioma: inglés
  • Enlaces
  • Resumen
    • N-Benzoyltryptamine (3), previously isolated from Myrtopsis myrtoidea and a new analogue, N-salicyloyltryptamine (5), were prepared by coupling tryptamine with benzoylchloride and methyl salicylate, respectively. Their structural elucidation was made by the usual spectroscopic methods and two-dimentional NMR techniques COSY, COBY and HMBC. N-salicyloyltryptamine (5) was submitted to pharmacological screening behavior, showing depressant effects

Los metadatos del artículo han sido obtenidos de SciELO Chile

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