Perspectiva hematológica en el tratamiento de pacientes con COVID-19: rol de los tratamientos antiinflamatorios

• Autores: Patricio Rojas, Mauricio Sarmiento
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 148, Nº. 11, 2020, págs. 1640-1646
• Idioma: español
• Títulos paralelos:
  • Anti-inflammatory therapies for SARS-COV2 infection from a hematological perspective
• Enlaces
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• Resumen

  • The pathophysiology of the inflammatory profile induced by SARS-COV2 infection has similarities with conditions of immune system activation with cytokine release such as hemophagocytic syndrome and some cases of acute graft-versus-host disease. There are encouraging results of clinical studies, performed with increasingly better methodological quality, supporting the use of targeted and specific anti-inflammatory therapy in selected groups of patients with COVID-19 with severe inflammation. In this review we describe the inflammatory pathophysiology of the disease and the recent findings about its treatment.