A non-centrosymmetric polymorph of 5-hydroxy-7-methoxy-2-phenylchroman-4-one

• IVÁN BRITO ^[1] ; MARIO J SIMIRGIOTIS ^[1] ; ANGHEL BRITO ^[1] ; MIRIAM RODRÍGUEZ WERNER ^[2] ; JORGE BÓRQUEZ ^[1] ; PETER WINTERHALTER ^[2] ; ALEJANDRO CÁRDENAS ^[3]
  1. [1] Universidad de Antofagasta Facultad de Ciencias Básicas Departamento de Química
  2. [2] Technische Universität Braunschweig Institut für Lebensmittelchemie
  3. [3] Universidad de Antofagasta Facultad de Ciencias Básicas Departamento de Física

  Mostrar afiliaciones +
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 60, Nº. 1, 2015, págs. 2864-2866
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • The bioactive compound 5-hydroxy-7-methoxy-2-phenylchroman-4-one (pinostrobin, I), was isolated from aerial parts of Nolana ramossisima I.M. Johnst., a Chilean endemic species, using a combination of medium pressure column chromatography and high speed countercurrent liquid-liquid chromatography (HSCCC). The compound crystallized as a non-centrosymmetric polymorph in the orthorhombic chiral space group P2(1)2(1)2(1). Its structure had been previously reported by Shoja (Acta Cryst. C45, 828, 1989) and Yamovoi et al. (Khim. Prir. Soedin (5), 361, 2001) in the centrosymmetric space groups Pbca and P21/c, respectively.