Resumen de Toxicological studies in poultry consuming fumonisin from corn contaminated with Brazilian Amazonian flora
Oelton Ferreira Rosa Junior, Alex Sander Cangussu, Ana Patricia Silva, Kenia Rodrigues, Mellanie KC Felix, Túllio Teixeira Deusdará, Tatiani Ferreira, Helio S Brito, Kelvinson Viana, Eliane Macedo Sobrinho, Raimundo Wagner de Souza Aguiar, Gil R. Santos
- español
El hongo Fusarium verticillioides produce fumonisinas (FB1 y FB2), caracterizadas por ser las formas moleculares más frecuentemente producidas y con mayor toxicidad. La contaminación por fumonisinas es responsable de pérdidas sustanciales durante la cadena de producción de carne, por lo que se deben determinar los niveles seguros de estos compuestos. El estudio estuvo dirigido a establecer niveles seguros de FB1 en la producción avícola; para este fin, se utilizaron COBB 500 ®aves en lotes experimentales de maíz infectado durante la temporada 2015/2016 en Brasil. El grupo experimental incluyó 160 animales, divididos en dos grupos: Los T1 sin fumonisinas en la dieta (control); y el grupo T2 en el que el maíz estaba contaminado con 2,78 μg/g de fumonisina FB1.
- English
The fungus Fusarium verticillioides produces fumonisins (FB1 and FB2), characterized by being the most frequently produced molecular forms and with greater toxicity. Fumonisin contamination is responsible for substantial losses during the meat production chain, so the safe levels of these compounds must be determined. The study was directed to establish safe levels of FB1 in poultry production; for this purpose, were used COBB 500® birds on experimental lots of infected corn during the 2015/2016 season in Brazil. The experimental group included 160 animals, divided into two groups: The T1 without fumonisin in the diet (control); and the T2 group in which corn was contaminated with 2.78 μg/g of fumonisin FB1. Histopathological effects of liver, heart, and small intestine, and zootechnical parameters were measured in birds treated. We found that there were no significant differences between the birds treated and untreated after 21 days of exposure to each treatment; F-values > P-values (P<0,05) for feed intake and weekly weight gain. Taken together, our data showed that the concentration evaluated is safe in poultry and will contribute to the design of future clinical studies.
