Detección de huellas de selección en seis loci relacionados con la pigmentación en cabra

• B. Badaoui ^[1] ; A. Manunza ^[1] ; M. D'Andrea ^[1] ; F. Pilla ^[1] ; J. Capote ^[1] ; J. Jordana ^[1] ; A. Ferrando ^[1] ; A. Martínez ^[1] ; J.V. Delgado ^[1] ; V. Landi ^[1] ; M. Gómez ^[1] ; A. Pons ^[1] ; M. El Ouni ^[1] ; M. Amills ^[1] ; O. Vidal ^[1]
  1. [1] Universitat de Girona

     Universitat de Girona

     Gerona, España

     
• Localización: XV Jornadas sobre Producción Animal: 14 y 15 de mayo de 2013, Zaragoza / Jorge Hugo Calvo Lacosta (aut.), Isabel Casasús Pueyo (aut.), Margalida Joy Torrens (aut.), Javier Álvarez Rodríguez (aut.), Luis Varona Aguado (aut.), Begoña Panea Doblado (aut.), Carlos Calvete Margolles (aut.), Joaquim Barcells Teres (aut.), Vol. 2, 2013, ISBN 978-84-695-7684-7, págs. 604-606
• Idioma: español
• Títulos paralelos:
  • Signatures of selection in six color genes of goat
• Enlaces
  • Texto Completo Libro  1 (pdf)   2 (pdf) 
• Resumen

  • Our goal was to investigate if selection for this phenotype has left a detectable genetic signature in goats. Ten mutations, plus 2 other ones detected in previous studies were genotyped in 560 goats representing 18 breeds from Italy, Spain, Canary Islands and North Africa. We detected significant evidences of directional selection at the MC1R and KIT genes, and of balancing/purifying selection at TYR and TYRP2 loci. However, population structure and phylogeographic analyses, considering both neutral and non-neutral SNP, demonstrated that breeds cluster according to their geographic origin (and not to their coat color).