Estudio del perfil transcripcional de genes implicados en el metabolismo de los ácidos grasos de la leche en dos razas ovinas.

• A. Suárez Vega ^[1] ; B. Gutiérrez Gil ^[1] ; J.J. Arranz ^[1]
  1. [1] Universidad de León

     Universidad de León

     León, España

     
• Localización: XVI Jornadas sobre Producción Animal: 19 y 20 de mayo de 2015, Zaragoza / Javier Álvarez Rodríguez (aut.), Begoña Panea Doblado (aut.), Jorge Hugo Calvo Lacosta (aut.), Mireia Blanco Alibés (aut.), José Alfonso Abecia Martínez (aut.), Daniel Villalba Mata (aut.), María Ángeles Latorre Górriz (aut.), Vol. 2, 2015, ISBN 978-84-606-7969-1, págs. 462-464
• Idioma: español
• Títulos paralelos:
  • Study of the transcriptional profile of genes realted to the mammary gland fat metabolism in two ovine breeds.
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• Resumen

  • Sheep milk ranks the fourth position in terms of global milk production from different species. Most of the world’s sheep milk is processed into dairy products, mostly cheese. Milk lipid synthesis as well as fatty acid esterification and milk fat secretion have a special interest due to their influence in manufacturing and organoleptic properties in dairy products. In this study we performed a RNA-seq analysis in two different dairy sheep breeds in order to evaluate the transcriptional profile of some genes implicated in the mammary gland fat metabolism along lactation. The selected genes are: LPL and VLDL, implicated in the fatty acid uptake from blood; ACACA, FASN and SCD, implicated in de novo synthesis and fatty acid desaturation; BTN1A1 and XDN implicated in lipid droplet formation. None of the genes evaluated is significantly differentially expressed between the two breeds nor along lactation, but we can see changes in the expression profile. Mostly all of the genes analyzed increased their expression along lactation. SCD1, ACACA y XDH were the most abundant key genes measured, appearing to be key genes in milk fat metabolism.