Multicomponent Reactions: “Kinderleicht”

• Constantinos G. Neochoritis ^[1] ; Tryfon Zarganes-Tzitzikas ^[1] ; Kallia Katsampoxaki-Hodgetts ^[2] ; Alexander Dömling ^[1]
  1. [1] University of Groningen

     University of Groningen

     Países Bajos

     
  2. [2] University of Crete

     University of Crete

     Dimos Heraklion, Grecia

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 97, Nº 10, 2020, págs. 3739-3745
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A demonstration experiment of the synthesis of a novel tetrazole derivative via a multicomponent reaction (Ugi tetrazole four component reaction, UT-4CR) bearing a luminol moiety and a subsequent exploitation of its chemiluminescent properties is described. A complex product is generated in just one simple step, so simple that children can do it: “kinderleicht”, German for dead easy. Students are stimulated, inspired, and involved in a multilevel active learning process using the Steps to Inquiry framework as a metacognitive tool that raises student awareness regarding scientific process and prompts them to ask their own questions discussing the merits of a mechanism and evaluating its effectiveness before they start their own cycles of inquiry.