Silicone granulomatous lymphadenopathy and siliconomas of the breast

• Vaamonde, R. ^[1] ; Cabrera, J.M. ^[2] ; Vaamonde-Martín, R.J. ^[1] ; Jimena, I. ^[1] ; Marcos Martín, J. ^[1]
  1. [1] Universidad de Córdoba

     Universidad de Córdoba

     Cordoba, España

     
  2. [2] Red Cross Hospital

     Red Cross Hospital

     Dimos Athens, Grecia

     
• Localización: Histology and histopathology: cellular and molecular biology, ISSN-e 1699-5848, ISSN 0213-3911, Vol. 12, Nº. 4, 1997, págs. 1003-1011
• Idioma: inglés
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• Resumen

  • In the present study, two histologicallydistinct cases of granulomatous lymphadenitis induced by dimethylpolysiloxane (silicone polymer) implants were studied. Four and six years after implant, and following surgery for breast cancer, painful homolateral axillary adenopathies were observed and biopsied. In both cases, histological examination led to a diagnosis of "silicone-induced granulomatous adenitis" requiring removal of implants. Foreign-body granulomas (siliconomas) were observed in surrounding tissue with no apparent rupture of implant capsules; however, visible retraction, hardening and scattered calcifications were noted. The presence of silica was revealed by incineration of a number of biopsied lymph nodes, a technique not hitherto used in the study of this pathology. A review is offered of the literature available