Association between type 2 diabetes mellitus and the evolution of endodontic pathology
- Autores: Néstor Raúl Ríos Osorio, Hernan Darío Muñoz Alvear, Santiago Montoya Cañón, Silvia Restrepo, Sandra E. Aguilera Rojas, Oscar Javier Jiménez, Herney Andrés García Perdomo
- Localización: Quintessence International, ISSN-e 0033-6572, Vol. 51, Nº. 2, 2020, págs. 100-107
- Idioma: inglés
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Resumen
Objective: The purpose of the present study was to assess the influence of type 2 diabetes mellitus (DM) on the evolution of pulpal and periapical pathology.
Method and materials: Two reviewers independently conducted a systematic search for articles published between 1 January 2001 and 31 December 2018 on MEDLINE/PubMed, ISI Web of Science, and Scopus databases. An additional manual search was also carried out.
Results: Ten studies fulfilling the inclusion criteria were included in the review (two longitudinal studies with 1-year follow-up comparing the success of primary root canal treatment between type 2 diabetic patients and non-diabetic patients, and eight cross-sectional studies). Analysis of the ten studies showed that inadequate control of type 2 DM may predispose and influence the inflammatory pulpal and periapical disease evolution.
Conclusions: The present systematic review suggests that there are biologic bases to suggest that type 2 DM may act as a risk factor for developing an endodontic pathology, affecting the course of the disease in terms of susceptibility, prevalence, progression, and tissue healing capacity as a consequence of a disrupted immune response. However, more well-designed clinical investigations carrying out suitable research methodologies are needed to elucidate the influence of type 2 DM on the pulpal and periapical disease evolution.
