Immediate dental implants placed into infected sites present a higher risk of failure than immediate dental implants placed into non-infected sites: systematic review and meta-analysis

• Olavo-Barbosa de Oliveira-Neto ^[3] ; Cleidiel-Aparecido-Araújo Lemos ^[1] ; Fabiano-Timbó Barbosa ^[2] ; Célio-Fernando de Sousa-Rodrigues ^[2] ; Fernando-José Camello de Lima ^[2]
  1. [1] Universidade Estadual Paulista

     Universidade Estadual Paulista

     Brasil

     
  2. [2] Universidade Federal de Alagoas

     Universidade Federal de Alagoas

     Brasil

     
  3. [3] DDS, MSc student, Department of Morphology, Anatomy Area, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 24, Nº. 4 (July), 2019
• Idioma: inglés
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• Resumen

  • Alveolar infection is known as a risk factor for implant failure. Current meta-analysis on the theme could not prove statistically that immediate dental implants placed into infected sites have a higher risk of failure than immediate dental implants placed into non-infected sites. The purpose of this meta-analysis was to determine the effectiveness of immediate dental implants placed into infected versus non-infected sites.

    Seven databases were sought by two reviewers. Randomized or non-randomized clinical trials that compared the placement of dental implants into infected versus non-infected sites were eligible for the study. Exclusion criteria were: papers in which the survival rate was not the primary outcome; papers without a control group; studies with less than one year of follow-up; studies whose patients did not receive antibiotic therapy; studies with medically compromised patients; duplicated papers. Risk of bias assessment was performed with the Cochrane Collaboration tool.

    Of the 3.253 initial hits, 8 studies were included in both qualitative and quantitative synthesis (kappa=0.90; very good agreement). Forest plot for implant failure showed that immediate implants placed into infected sites presented a statistically significant risk of failure that is almost 3 times higher than when placed into non-infected sites (risk ratio= 2.99; 95% confidence interval: 1.04, 8.56; p= 0.04; 935 implants; i2= 0%). Peri-implant outcomes showed no statistical difference.

    Immediate dental implants placed into infected sites presented a statistically significant higher risk of failure than immediate dental implants placed into non-infected sites. Peri-implant outcomes were not statistically affected in this intervention.