Pigmented squamous cell carcinoma in situ: report of a new case and review of the literature

• Fabiana Martins ^[2] ; Florence-Zumbaio Mistro ^[4] ; Sergio Kignel ^[3] ; Michelle Palmieri ^[1] ; Alan-Motta do Canto ^[1] ; Paulo-Henrique Braz-Silva ^[1]
  1. [1] Universidade de São Paulo

     Universidade de São Paulo

     Brasil

     
  2. [2] Universidade de Santo Amaro

     Universidade de Santo Amaro

     Brasil

     
  3. [3] PhD, MDS, DDS, Division of Oral Diagnosis, Department of Dentistry, Herminio Ometto Fondation – UNIARARAS, Araras, SP, Brazil
  4. [4] MDS, DDS, Division of Oral Diagnosis, Department of Dentistry, Herminio Ometto Fondation – UNIARARAS, Araras, SP, Brazil

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• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 9, Nº. 11 (November ), 2017, págs. 1362-1365
• Idioma: inglés
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• Resumen

  • Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful black and red lesion located on the right aspect of the oropharyngeal isthmus. After incisional biopsy, the resulting sample was described as a pigmented squamous cell carcinoma in situ, a diagnosis further confirmed by immunohistochemical analysis. Treatment consisted in total excision of the lesion, and no recurrence was observed after a 30-month follow-up. Clinicians and pathologists should be aware of PSCCIS as a differential diagnosis of melanoma, a lesion which significantly increases the morbidity and mortality rates among these patients.