Clinical trials in orthodontics I: demographic details of clinical trials published in three orthodontic journals between 1989 and 1998

• Autores: Jayne E Harrison
• Localización: Journal of orthodontics, ISSN-e 0301-228X, ISSN 1465-3125, Vol. 30, Nº. 1, 2003, págs. 25-30
• Idioma: inglés
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• Resumen

  • Aim: To test the hypothesis that there is insufficient evidence available, from clinical trials, to allow evidence-based decisions to be made on the effectiveness of orthodontic treatment.

    Objectives: To identify reports of orthodontic clinical trials and assess their demographic characteristics.

    Design: A retrospective, observational study.

    Setting: The American Journal of Orthodontics and Dentofacial Orthopedics, British Journal of Orthodontics, and European Journal Orthodontics.

    Data source: Clinical trials published between 1989 and 1998.

    Method: A hand-search was performed to identify all clinical trials. The journal and year of publication, research method, interventions, and sample size of the trials reported were recorded.

    Results: One-hundred-and-fifty-five trial reports were identified of which 56 (36.1%) were published from 1989 to 1993 and 99 (69%) from 1994 to 1998. Ninety-nine (69%) reports were published in the AJO-DO, 18 (11.6%) in the BJO and 38 (24.5%) in the EJO. Eighty-five (54.8%) were reports of randomized controlled trials and 70 (45.2%) of controlled clinical trials. The interventions most frequently assessed were bonding materials (21.9%), growth modification treatments (21.3%), and oral hygiene procedures (9.0%). The median sample size was 32 (IQR 19.5, 50).

    Conclusion: There is sufficient evidence available from clinical trials to warrant doing systematic reviews of orthodontic clinical trials to aid decision-making.