Evaluation of the Postmortem Glucose and Glycogen Levels in Hepatic, Renal, Muscle, and Brain Tissues:: Is It Possible to Estimate Postmortem Interval Using These Parameters?

• Alper Gümüs ^[1] ; Burak Gümüs ^[2] ; Erdal Ozer ; Esma Yücetas ^[1] ; Ugur Yücetas ^[3] ; Emin Düz ^[1] ; Soner Sarı ^[1] ; Macit Koldas ^[1]
  1. [1] Medical Biochemistry Laboratory Haseki Training and Research Hospital Istanbul Turkey
  2. [2] Kastamonu Office Turkey Forensic Medicine Institution Kastamonu Turkey
  3. [3] Istanbul Training and Research Hospital Urology Department Istanbul Turkey

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• Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 61, Nº. Extra 1, 2016, págs. 144-149
• Idioma: inglés
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• Resumen

  • The aim of our study was to investigate the postmortem levels of glucose and glycogen in hepatic, renal, muscle, and brain tissues and then examine the changes in those levels that could be useful for estimating postmortem interval. We established an animal model.

    Seventy female BALB/c albino mice were used in this study. After being sacrificed, the mice were randomly divided into six groups according to time elapsed since death (Group 1: 0 h; Group 2: 12 h; Group 3: 24 h; Group 4: 36 h; Group 5: 48 h; and Group 6: 60 h). Glucose levels were significantly different between groups for all tissues studied. Slope of the change per unit time was higher for the hepatic glucose levels. Based on these results, it is possible to estimate postmortem interval using postmortem glucose levels in hepatic tissue. Tissue-specific assessment may contribute valuable information to postmortem interval studies