Resumen de Effects of Bioactive Glass on Bone Augmentation Within a Titanium Cap in Rabbit Parietal Bone

Tetsuya Nishida, Yutaka Yamada, Masakazu Murai, Yuka Shimizu, Maiko Oshikawa, Koichi Ito

• Background: The condition of alveolar bone influences the success and subsequent esthetics of implant treatment. This study investigated the early effects of bioactive glass (BG) on bone augmentation within a hemispherical titanium cap in rabbit parietal bone.

  Methods: Twelve adult male Japanese white rabbits were used. One titanium cap (test site) was packed with BG in a collagen gel, and the other (control site) was packed with the collagen gel alone. After 1 and 3 months, animals were euthanized, and the experimental area was examined using fluorescence and light microscopy.

  Results: Newly generated bone was observed at 1 and 3 months of healing. Although bone was also generated without BG, newly mineralized bone was generated sooner with BG present for guided bone augmentation than without BG. At 1 and 3 months, the BG was not bioabsorbed completely, and some particles remained.

  Conclusion: New bone is generated at an early stage of bone formation using BG for bone augmentation.