Diabetic Ketoacidosis at Diagnosis Influences Complete Remission After Treatment With Hematopoietic Stem Cell Transplantation in Adolescents With Type 1 Diabetes

• Autores: Weiqiong Gu, Jiong Hu, Weiqing Wang, Lirong Li, Wei Tang, Shouyue Sun, Weijuan Cui, Lei Ye, Yifei Zhang, Jie Hong, Guang Ning
• Localización: Diabetes care, ISSN-e 0149-5992, Vol. 35, Nº. 7, 2012, págs. 1413-1419
• Idioma: inglés
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• Resumen

  • According to the response of the patients to AHSCT, a 100% reduction in the daily insulin dose (insulin free) was defined as a complete remission (CR). In a Finland study, low serum C-peptide concentrations, a high requirement of exogenous insulin, a low prevalence of remission, and high glycated hemoglobin concentrations were observed during the follow-up period in the group of probands having DKA at diagnosis of type 1 diabetes (24).