Resumen de Enfermedad severa de inclusiones de una mujer inmunizada antes de la gestación

Ana Villalba, M. de Marino, Alexandra Henríquez, M. Belloso, A. Tejerizo-Garcia

• Due to detection of fetal microcephaly at 24 weeks gestation, we performed an amniocentesis at 29 weeks with chromosomal analysis and polymerase chain reaction (PCR) to investigate the presence of viral contamination. Cytomegalovirus (CMV) infection was confirmed by PCR, although the mother had preconceptional CMV immunity. The fetus showed classical CMV inclusion disease. Recent publications explain similar observations by the variability of viral strains. These findings highlight the importance of being alert to ultrasonographic signs of CMV reinfection in pregnant womwn with preconceptual immunuty.