Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico

• Felipe Suárez H ^[2] ; Daniela Urrutia E ^[2] ; Felipe Canales P ^[1] ; Camila Gutiérrez O ^[1]
  1. [1] Universidad Austral de Chile

     Universidad Austral de Chile

     Valdivia, Chile

     
  2. [2] Hospital Base de Osorno Departamento de Neurología
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 144, Nº. 9, 2016, págs. 1226-1229
• Idioma: español
• Títulos paralelos:
  • Neuromyelitis optica presenting concomitantly with systemic lupus erythematosus: Report of one case
• Enlaces
  • Texto completo
• Resumen

  • Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on immunosuppressive drugs. Immunomodulators are contraindicated. We report a previously healthy 35-year-old man, presenting with NMO concomitantly with systemic lupus erythematosus. His evolution was torpid with three outbreaks in the 10 months after the diagnosis, requiring a first-line therapy with methylprednisolone and cyclophosphamide and then a second-line therapy with rituximab.