Resumen de Tissue unit-ed: lung cells team up to drive alveolar macrophage development

Charlotte L. Scott, Martin Guilliams

• Using single-cell RNA sequencing of both immune and non-immune cells in the developing lung, Cohen et al. map candidate cell-cell interactions during alveolar macrophage development. This revealed potential cross-talk between epithelial cells, ILC2s, basophils, and the developing macrophages, which were validated both in vitro and in vivo.