Resistance training status modifies inflammatory response to explosive and hypertrophic resistance exercise bouts

Johanna K. Ihalainen ^[1] ; Juha P. Ahtiainen ^[1] ; Simon Walker ^[1] ; Gøran Paulsen ^[4] ; Harri Selänne ^[2] ; Mari Hämäläinen ^[1] ; Eeva Moilanen ^[3] ; Heikki Peltonen ^[1] ; Antti A. Mero ^[1]
1. [1] University of Jyväskylä
  
  University of Jyväskylä
  
  Jyväskylä, Finlandia
2. [2] Norwegian School of Sport Sciences
  
  Norwegian School of Sport Sciences
  
  Noruega
3. [3] University of Tampere
  
  University of Tampere
  
  Tampere, Finlandia
4. [4] The Norwegian Olympic and Paralympic Committee and Confederation of Sports. Oslo. Norway
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Localización: Journal of physiology and biochemistry, ISSN-e 1877-8755, ISSN 1138-7548, Vol. 73, Nº. 4, 2017, págs. 595-604
Idioma: inglés
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Resumen
- The purpose of the present study was to examine the immediate and prolonged immune response in circulating cytokine and adipocytokine concentrations after two different resistance exercise bouts: hypertrophic (HYP1, 5 × 10, 80% of 1RM) and maximal explosive (POW1, 10 × 5, 60% of 1RM) resistance exercise bouts and how 12 weeks of resistance training (RT) modifies these responses (HYP2, POW2). Eight men completed the study. RE-induced interleukin-6 (IL-6), interleukin-1β (IL-1β), interleukin-1 receptor antagonist (IL-1ra), monocyte-chemoattractant protein-1 (MCP-1), leptin, resistin, and adiponectin were measured before (PRE) and immediately (POST0), 24 (POST24) and 48 (POST48) hours after RE bouts before and after RT. In the untrained state, IL-6 increased immediately after RE in HYP1 (p = 0.002) and in POW1 (p = 0.003) whereas no changes were observed after RT. Similar results were observed in IL-1β, whereas conversely, IL-1ra increased only after RT in HYP2 and POW2 (p < 0.05). Resistin increased before RT in HYP1 and in POW1 (p = 0.011 and p = 0.003, respectively), but after RT, significant responses were not observed. Interestingly, in HYP2, MCP-1 increased significantly at POST24 (p = 0.009) and at POST48 (p = 0.032) only following RT. The present study shows that RT modifies RE-induced cytokine responses towards an anti-inflammatory direction.